Gilbert Grape is a small-town young man with a lot of responsibility. Chief among his concerns are his mother, who is so overweight that she can't leave the house, and his mentally impaired younger brother, Arnie, who has a knack for finding trouble. Settled into a job at a grocery store and an ongoing affair with local woman Betty Carver, Gilbert finally has his life shaken up by the free-spirited Becky.

Ana meets Rafa in a chance encounter and they embark on a road trip to try and save him from bankruptcy, or worse.

Richard is assigned public service after crashing his homemade aircraft, leading him to meet Jane, a young woman dying of motor neuron disease. Jane wishes to be de-flowered before her death; Richard declines, struggling to maintain his relationship with his girlfriend, but offers to help pay for a gigolo to do the deed.

Handsome but backward gardener Tim Melville has a new woman in his life. She is Mary, his widowed employer, a woman who had given up on love until she had found Tim. At first they are friends. But soon they become lovers, as Mary, drawn to Tim's innocence and magnetism, begins to teach him all about life - and love.

A suicidal young man is committed to a Dublin psychiatric hospital where he meets new friends who greatly influence his life.

When his only friend dies, a man born with dwarfism moves to rural New Jersey to live a life of solitude, only to meet a chatty hot dog vendor and a woman dealing with her own personal loss.

Bridget Jones navigates life as a widow and single mum with the help of her family, friends, and former lover, Daniel. Back to work and on the apps, she's pursued by a younger man and maybe – just maybe – her son's science teacher.

Two drifters bum around, visit earthy women and discuss opening a car wash in Pittsburgh.

A wheelchair-bound singer and her best friend embark on a roadtrip to Memphis.

A mentally ill young woman finds her love in an eccentric man who models himself after Buster Keaton.

A man in his mid-20s, still living at home with his mother and stepfather, puts all his eggs in one basket: the girl who works at his local coffee shop. The problem is, she has a serious boyfriend. As they become closer, the line between friendship and intimacy is blurred, and the situation forces both to examine where they are in their lives.

A car accident and shifting affections test the bond between a married couple.

In Oklahoma, Agnes, a lonely waitress living in an isolated and dilapidated roadside motel, meets Peter, a quiet and mysterious man with whom she establishes a peculiar relationship.

Having suffered a tragedy, Ben becomes a caregiver to earn money. His first client, Trevor, is a hilarious 18-year-old with muscular dystrophy. One paralyzed emotionally, one paralyzed physically, Ben and Trevor hit the road on a trip into the western states. The folks they collect along the way will help them test their skills for surviving outside their calculated existence. Together, they come to understand the importance of hope and the necessity of true friendship.

Upon his release from a mental hospital following a nervous breakdown, the directionless Anthony joins his friend Dignan, who seems far less sane than the former. Dignan has hatched a harebrained scheme for an as-yet-unspecified crime spree that somehow involves his former boss, the (supposedly) legendary Mr. Henry.

A mentally challenged girl proves herself to be every bit as capable as her "perfect" sister when she moves into an apartment and begins going to college.

In trouble with the local authorities, Mabel Simmons, notoriously known as Madea, is on the run from the law. With no place to turn, she moves in with her friend Bam who is recovering from surgery. Unbeknownst to Bam however, Madea is only using the "concerned friend" gag as a way to hide out from the police.

Phillip is a wealthy quadriplegic who needs a caretaker to help him with his day-to-day routine in his New York penthouse. He decides to hire Dell, a struggling parolee who's trying to reconnect with his ex and his young son. Despite coming from two different worlds, an unlikely friendship starts to blossom.

The story of Bea Johnson from birth to graduation as she navigates life with an intellectually disabled parent and an extended family who can't quite agree on the best way to help.

After learning that his terminally ill wife has six months to live, a man welcomes the support of his best friend who moves into their home to help out.