Tom, complete with mortarboard, is teaching a kitten the basics: "cats chase mice." But Jerry keeps subverting this lesson at every opportunity.

The popular cartoon cat and mouse are thrown into a feature film. The story has the twosome trying to help an orphan girl who is being berated and exploited by a greedy guardian.

Tom's new book on "how to catch a mouse" doesn't prove too helpful against Jerry; actually, Jerry seems to make better use of it than Tom.

Tom chases Jerry into a bottle of invisible ink, and the now-invisible Jerry proceeds to have fun torturing Tom.

Tom inherits $1,000,000 from an eccentric aunt on the condition that he not harm any living thing - even a mouse. And guess which mouse keeps following him around and pointing this out to him?

Jerry crashes a vase onto Tom's head, which gets Mammy to throw Tom out. Jerry at first revels in his freedom, but soon tires of this, and, under a flag of truce, hatches a plan with Tom.

A moment after a bottle of white shoe polish pours on Jerry, Tom hears on the radio that a white mouse, having swallowed an explosive, has escaped from an experimental laboratory and that slightest jar of the mouse could cause it to explode and blow up the entire city. It is then that Tom notices now-white Jerry and concludes it's the escapee.

Jasper is given an ultimatum by his master: break one more thing and you're out. Rodent Jerry does his best to make sure that his tormentor "gets the boot".

Tom invites Toots to an elegant dinner. However, he's made the mistake of trying to put Jerry to work, as a serving boy, a corkscrew, and other tasks. Jerry puts up with a little of this, but mostly gets revenge on Tom.

Maurice is a streetwise ginger cat who comes up with a money-making scam by befriending a group of self-taught talking rats. When Maurice and the rodents meet a bookworm called Malicia, their little con soon goes down the drain.

Mammy Two-Shoes replaces Tom with a younger cat who is a lightning-quick mouser. Tom and Jerry form an alliance in order to get rid of this dangerous newcomer.

Tom drowns in a lake and sinks to the bottom. There, he finds a mermouse, which he tries to capture and eat.

Tom subjects Jerry to his usual harassment; but the cat finds a new enemy, and the mouse finds a new friend, in the canary of the house.

Tom hears a ghost story on the radio and is spooked by it; Jerry notices this and takes advantage of it, using a variety of tricks to scare Tom.

Jerry agrees to help an escaped circus lion, whose first need is food. But first they'll have to evade Tom, who heard the news bulletin and is armed with a shotgun.

Someone drops off three cute little kittens; Tom is put in charge of them while Mammy goes shopping. But behind her back, the three little angels are real devils.

Mammy Two-Shoes threatens to throw Tom out of the house if he makes a mess. Jerry sees an opportunity to rid himself of his feline nemesis.

Jerry and his diapered little mouse friend flood the kitchen, then use the freezer to turn it into a skating rink. Even though Tom finds a pair of ice skates, the mice have no problem outmaneuvering him.

Jerry Mouse gets tired of living the country life and decides to head to the big city. However, the experience doesn't turn out quite like Jerry had expected.

Tom steals an egg from a mother duck's nest, but soon the resultant hatchling runs away from the cat and into a mouse hole, where it finds an able protector in Jerry.