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Set in the changing world of the late 1960s, Susanna Kaysen's prescribed "short rest" from a psychiatrist she had met only once becomes a strange, unknown journey into Alice's Wonderland, where she struggles with the thin line between normal and crazy. Susanna soon realizes how hard it is to get out once she has been committed, and she ultimately has to choose between the world of people who belong inside or the difficult world of reality outside.

Jack Slavin is an environmentalist with a heart condition who lives with his daughter, Rose, on an isolated island. While Jack fights against developers who wish to build in the area, he also craves more contact with other people. When he invites his girlfriend, Kathleen, and her sons, Rodney and Thaddius, to move in, Rose is upset. The complicated family dynamics makes things difficult for everyone in the house.

A shy but ambitious film student falls into an intense, emotionally fraught relationship with a charismatic but untrustworthy older man.

A troubled young woman becomes obsessed with her mysterious new neighbor, who bears a striking resemblance to the girl's dead mother.

On the outside, Helen has it all – a loving family and a successful career – but when her suppressed mental illness resurfaces, the world crumbles around her. Crippled by depression, Helen finds solace through her friendship with Mathilda, a kindred spirit struggling with bipolar disorder.

With her life crashing down around her, Linda attempts to navigate her child's mysterious illness, her absent husband, a missing person, and an increasingly hostile relationship with her therapist.

After inheriting a remote Montana house, Jackson moves there from New York with his partner Grace, and the couple soon welcome a child. As Jackson becomes increasingly absent and rural isolation sets in, Grace struggles with loneliness, creative frustration, and unresolved emotional wounds. What begins as an attempt at renewal gradually turns into an intense psychological descent, placing strain on their relationship and exposing the fragile balance between love, identity, and motherhood.

A tenacious attorney uncovers a dark secret that connects a growing number of unexplained deaths to one of the world's largest corporations. In the process, he risks everything — his future, his family, and his own life — to expose the truth.

A twice-divorced mother of three who sees an injustice, takes on the bad guy and wins -- with a little help from her push-up bra. Erin goes to work for an attorney and comes across medical records describing illnesses clustered in one nearby town. She starts investigating and soon exposes a monumental cover-up.

Vada Sultenfuss is obsessed with death. Her mother is dead, and her father runs a funeral parlor. She is also in love with her English teacher, and joins a poetry class over the summer just to impress him. Thomas J., her best friend, is "allergic to everything", and sticks with Vada despite her hangups. When Vada's father hires Shelly, and begins to fall for her, things take a turn to the worse...

Isolated on a remote property, 16-year-old Claudia finds her world transformed when a spirited girl named Grace wanders into her garden.

In a suburban landscape, the lives of several families interlace with loss, despair and personal crisis. Esther Gold has lost focus on all but caring for her comatose son, Paul, and neglects her daughter and husband. Lawyer Jim Train is devoted to his career, not his family. Helen Christianson wants to find a new spark in life, while Annette Jennings tries to rebuild hers.

Zach Riley is a psychiatrist, who leaves a job at a prestigious university, to take up a job at the privately run mental institution, Millwood. What he doesn't reveal at the time of his appointment is that this was the very place where his novelist father, T.L. Pierson, spent many years of his life.

A guarded woman finds out she's dying of cancer but, when she meets her match, the threat of falling in love is scarier than death.

A misanthropic author, a single mother and waitress, and a gay artist form an unlikely friendship after the artist is assaulted in a robbery.

A teenager who's lived a sheltered life because she's allergic to everything, falls for the boy who moves in next door.

A psychotherapist helps a law student cope with schizophrenia in one of five interconnected tales dealing with mental illness.

94-year-old Eleanor Morgenstein tries to rebuild her life after the death of her best friend. As a result, she moves back to New York City after living in Florida for decades.

A wealthy woman from Manhattan's Upper East Side struggles to deal with her new identity and her sexuality after her husband of 16 years leaves her for a younger woman.

After a bad breakup with his girlfriend leaves him heartbroken, Carter Webb moves to Michigan to take care of his ailing grandmother. Once there, he gets mixed up in the lives of the mother and daughters who live across the street.