When Dr. Marcus Sommers realizes that he and his troubled, estranged brother David may be prone a fatal brain disease that runs in their family, he decides to make peace with his sibling, and invites him on a trip to the Rockies. There, the brothers bond over their shared enthusiasm for cycling and decide to enter a grueling bike race through the mountains. However, Marcus' health soon begins to fail, and David must compete without his brother at his side.

An Irish sports journalist becomes convinced that Lance Armstrong's performances during the Tour de France victories are fueled by banned substances. With this conviction, he starts hunting for evidence that will expose Armstrong.

Tom and Mae Garvey are a Tennessee farming couple battling violent floods to save their land. In addition to natural disasters, the Garveys fight to stop a selfish land developer and a local corporation from foreclosing on their farm. While Mae stays at home to care for their children and tend to the crops, Tom finds work as a scab at a steel mill to preserve his family's property.

Two kids, Dylan and Kylie, run away from home on Christmas Day and spend a night of magic and terror on the streets of inner-city Dublin.

An aging Tennessee farmer returns to his homestead and must confront a family betrayal, the reappearance of an old enemy, and the loss of his farm.

Evangelist Carlton Pearson is ostracized by his church for preaching that there is no Hell.

Unhappily married, Julia Sturges decides to go to America with her two children on the Titanic. Her husband, Richard also arranges passage on the luxury liner so as to have custody of their two children. All this fades to insignificance once the ship hits an iceberg.

Gentle and broken, a homeless man fights others on video for money but soon finds comfort in an unlikely friend and the lost diary of a young girl.

Sarah and David are single strangers who meet at a mutual friend’s wedding and soon, through a surprising twist of fate, find themselves on a funny, fantastical, sweeping adventure together where they get to re-live important moments from their respective pasts, illuminating how they got to where they are in the present... and possibly getting a chance to alter their futures.

After tragedy strikes Henry and Penny, he befriends a tenacious young girl and discovers she is constructing a raft to sail across the Atlantic to find her lost father. Together, along with some unlikely friends, they set forth to construct the vessel and subsequently rebuild their lives.

The legendary Roberto Duran and his equally legendary trainer Ray Arcel change each other's lives.

Matt Ryder is convinced to drive his estranged and dying father Benjamin Ryder cross country to deliver four old rolls of Kodachrome film to the last lab in the world that can develop them before it shuts down for good. Along with Ben's nurse Zooey, the three navigate a world changing from analogue to digital while trying to put the past behind them.

After suffering a personal tragedy, and desperate for justice, Jacob Kanon, a veteran New York City police detective, embarks on the search for a twisted killer who is leaving a bloody trail of elaborate murders across Europe.

In a suburban landscape, the lives of several families interlace with loss, despair and personal crisis. Esther Gold has lost focus on all but caring for her comatose son, Paul, and neglects her daughter and husband. Lawyer Jim Train is devoted to his career, not his family. Helen Christianson wants to find a new spark in life, while Annette Jennings tries to rebuild hers.

Newly widowed Frank Fogle embarks on a journey to Ireland to scatter his late wife’s ashes. His estranged son, Sean, recently released from prison, agrees to join only when his father promises that they’ll never see each other again following the trip. After revelations surface about an old flame of Frank’s wife and a charming hitchhiker with plans of her own intervenes, father and son find themselves drawn together in unexpected ways.

In New York City, a young girl is caught in the middle of her parents' bitter custody battle.

A burned-out paramedic tries to survive his last 24 hours on the job while training a new recruit.

Jonathan is a young man with a strange condition that only his brother understands. But when he begins to yearn for a different life, their unique bond becomes increasingly tested.

A poor, struggling South Carolinian mother and daughter face painful choices with their resolve and pride. Bone, the eldest daughter, and Anney her tired mother, grow both closer and farther apart: Anney sees Glen as her last chance.

Middle-aged Jem sets out from his suburban home on a journey into the woods, where he reconnects with his estranged hermit brother Ray. Bonded by a mysterious, complicated past, the men share a fraught, if occasionally tender relationship—one that was forever altered by shattering events decades earlier.