The FBI team hunts a dangerous enemy operative, and a deadly new foe emerges.

The entire intelligence community is put in jeopardy when Remi co-opts an FBI case.

Patterson and Rich DotCom take the reigns as the FBI team faces an explosive threat.

A decoded tattoo leads the team to a mysterious cache of dolls which turn out to be vehicles for biological weapons being sent around the world and now to the FBI. Jane exploits the fear of the weapons to advance her own plan to recover Shepherd.

A blast from Rich DotCom's past sends the FBI team after a deadly terrorist plot.

The team is drawn into dangerous political intrigue when a tattoo points to someone from Weitz's past.

Remi races against the ever-worsening ZIP poisoning to enact her ultimate plan.

The team's desperate gambit to get Jane back puts her head-to-head with Remi.

Reade confronts Zapata, while the team follows a lead to a potential cure for Jane.

The murder of a best-selling true crime novelist sends Jane and the team on a hunt for a serial killer detailed in the author's final manuscript, which also features lightly fictionalized versions of the FBI team.

Roman's clues lead to a billionaire hypochondriac with stem cells that could cure Jane, who is now on her deathbed. Patterson and Rich offer to trade the Book of Secrets for the stem cells -- but first they'll have to get it.

Jane and Weller's romantic getaway is cut short when the team must stop Madeline Burke's plans to blow up a building and crash a plane that turns out to be more than the average commercial airliner.

An active bomber forces the team to delve into a case from their past.

Jane's past with Shepherd and Sandstorm both helps and hurts the team's efforts to stop the sale of a device that will weaponize stolen plutonium.

Madeline escalates her plan, but the team isn't the only one chasing her down. Rich grows concerned for Boston’s well-being, and Jane seeks help from a familiar enemy.

The team races against the clock to save one of their own after Dominic enacts a nightmarish scheme in a bid for Madeline’s freedom. Tensions soar with Madeline as she makes her own demands.

Patterson's father, Bill Nye, returns for a case that pits the team against a pestiferous foe. Zapata goes rogue with an old friend. Jane and Weller continue their search for the hooded figure.

The team discovers an international conspiracy when a deadly weapon is stolen, Jane supports Weller when someone from his past dredges up painful memories, and Patterson and Rich contend with their newly released hacker accomplice.

A horrifying and vengeful villain threatens the FBI. Weller considers his priorities. Zapata and Reade try to navigate their living situation. Patterson explores a budding interest.

Dominic begins to enact Madeline's cataclysmic scheme as the team rushes to stop him. Tensions rise as past secrets begin to unravel.

The team sets out on an international mission to stop an attack from spreading. Madeline attempts to turn the tables as internal conflict threatens relationships within the team.