When billionaire Lance Durand's life is threatened, Alex Cross is called into action. But to find the killer, Cross must discover why someone would want to murder the man that feeds America.

A break in the investigation brings the team to Chicago, following the man with the haunting grin from surveillance footage. Meanwhile, Kayla's personal mission encounters a tragedy.

After finding clues in the subway, Cross' team tracks the suspect to Texas where they must work with Homeland Security to uncover another criminal enterprise.

Two vigilantes meet in a Florida hotel room, and plans are hatched to exact justice. But when their connection endangers both their lives, an impossible decision is made: only one can live.

Cross decodes the evidence to learn the vigilante is killing people in a specific order. He rushes to save the next person on the list, before it's too late.