Richard is irritated by a Karen who follows him with her dog, and she subsequently does the same to Cameron.

Karen returns with a new dog named Charlie and attempts to enter restaurants and businesses, only to discover that she is obliged to let Charlie go.

Karen's dogs, Milo and Charlie, have transformed into humans and fled from her home, causing Karen distress.

Karen develops a crush on Frederick, and they begin dating soon after, making Frederick Karen's first boyfriend.

Karen recognizes Milo and Charlie in their human forms after two days of not seeing them, but they are unfamiliar to her.

Milo and Charlie, who were formerly dogs but have now developed into people and are older than Karen, are no longer her property, although she believes differently.

Karen's dog, Sophia, has ran away from Karen after drinking a juice that changed her into a person, and she subsequently becomes Milo's girlfriend since she finds him attractive.

Officer Smith begs Tariq to become a substitute teacher since he has taken a week off from being a police officer.