Eighteen months after the events of season five, Nina and the Proudman clan are shaken by tragedy when a family gathering results in explosive revelations.

Nina and her St Francis colleagues are introduced to the flirtatious and suave new Director of Education, Dr Angus Freeman. Meanwhile, Leo has some shock news in store for Nina.

Nina gets to know St Francis' alleged "pantsman" Dr Angus Freeman better, with his behaviour leading her to do something out of character.

At St Francis, Nina deals with the fallout from a date. Meanwhile, Clegg and Cherie's relationship is put to the test as they find themselves suffering from a crisis of confidence.

The staff at St Francis are shaken by a public relations crisis at the hospital and Nina finds herself clashing with Harry Crewe, the consultant brought in to deal with the issue.

The staff at St Francis are shocked when an earlier PR crisis explodes into something far more serious. Nina sees a new side to Harry and is rocked by a visitor from Patrick's past.

Dr Patrick returns in Nina's fantasy as she grapples with a dilemma which has major consequences for everyone involved, including Billie.

Nina's attempt to do something for Billie spirals into a huge decision which could impact Nina's life forever and threatens to tear the two sisters apart.

Nina's relationship with Harry is tested when she makes a life-altering decision regarding Patrick.